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Vitamin B12: the essential nutrient with a complicated cancer link

Theoretical interactions include: SAM/SAMe supplements : NNMT inhibition preserves SAM

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This just-formed superoxide, together with its reduced metabolites, can interact with a great number of different naturally occurring body biomolecules, at least partially leading to the development of many diseases such as cardiovascular disease, cancer, chronic inflammation, dementia, and amyotrophic lateral sclerosis, among others [140,141]